Mesh and Simulation Time
As far as the results are concerned, the finer the mesh, the better. However, a very fine mesh has a large number of mesh cells and with this a large number of unknowns to be solved. Every increase of unknowns extends the need of memory and simulation time.
For the increase of simulation time, there are two different mechanisms. One is quite obvious: the more unknowns that are present, the more operations must be computed. The other mechanism is caused by the properties of the solver.
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See also
Mesh Generation Overview (Hexahedral), Mesh Generation Overview (Tetrahedral), Mesh View (Hexahedral), Mesh View (Tetrahedral), Mesh Properties (Hexahedral), Mesh Properties (Tetrahedral), Adaptive Mesh Refinement (Hex), Adaptive Mesh Refinement (Tet), Which Mesh to Use